BDBM553353 N-[4-fluoro-5-[2-[rac-(2R,6S)-2,6- dimethylmorpholin-4- yl]pyrimidin-5-yl]-2-[rac- (3S)-3-[ethyl(methyl)amino] pyrrolidin-1-yl]phenyl]-1- methyl-6-oxo-4-(trifluoromethyl) pyridine-3-carboxamide::US11319299, Example 427

SMILES CCN(C)[C@@H]1CCN(C1)c1cc(F)c(cc1NC(=O)c1cn(C)c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1C[C@H](C)O[C@H](C)C1

InChI Key InChIKey=VCDKNSAHIQDQGN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553353   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553353BDBM553353(N-[4-fluoro-5-[2-[rac-(2R,6S)-2,6- dimethylmorphol...)
Affinity DataKd:  5.59nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent