BDBM553373 4-(difluoromethyl)-N-[4- fluoro-5-(3-fluoro-4- morpholin-4-ylphenyl)-2- [rac-(3R)-3,4- dimethylpiperazin- 1-yl]phenyl]-6-oxo-1H- pyridine-3-carboxamide::US11319299, Example 448

SMILES C[C@H]1CN(c2cc(F)c(-c3ccc(N4CCOCC4)c(F)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)F)CCN1C

InChI Key InChIKey=VPNIKBUGBQZCMO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553373   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553373BDBM553373(4-(difluoromethyl)-N-[4- fluoro-5-(3-fluoro-4- mor...)
Affinity DataKd:  1.01nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent