BDBM553378 4-fluoro-N-[4-fluoro-5- [2-[rac-(2R)-2- methylmorpholin-4- yl]pyrimidin-5-yl]-2-[rac- (3S,5R)-3,4,5- trimethylpiperazin- 1-yl]phenyl]-2- (trifluoromethyl)benzamide::US11319299, Example 453

SMILES C[C@H]1CN(CCO1)c1ncc(cn1)-c1cc(NC(=O)c2ccc(F)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=YHRUDJMQAFXZEQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553378   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553378BDBM553378(4-fluoro-N-[4-fluoro-5- [2-[rac-(2R)-2- methylmorp...)
Affinity DataKd:  0.822nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent