BDBM553393 N-[4-fluoro-2-[rac-(3S)- 3,4-dimethylpiperazin-1- yl]-5-[2-[rac-(3R)-3- methylmorpholin-4-yl] pyrimidin-5-yl]phenyl]-6- oxo-4-(trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 468

SMILES C[C@@H]1COCCN1c1ncc(-c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c(N3CCN(C)[C@@H](C)C3)cc2F)cn1

InChI Key InChIKey=HEVWPLPEWXVHTO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553393   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553393BDBM553393(N-[4-fluoro-2-[rac-(3S)- 3,4-dimethylpiperazin-1- ...)
Affinity DataKd:  2.28nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent