BDBM553401 N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2-[rac-(3aR,6aR)-1- propyl-2,3,3a,4,6,6a- hexahydropyrrolo[2,3-c] pyrrol-5-yl]phenyl]-6- oxo-4-(trifluoromethyl)- 1H-pyridine-3-carboxamide::US11319299, Example 476

SMILES CCCN1CC[C@H]2CN(c3cc(F)c(-c4cnc(N5CCOCC5)nc4)cc3NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)C[C@H]21

InChI Key InChIKey=JZLWCFLWIODPLY-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553401   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553401BDBM553401(N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...)
Affinity DataKd:  9.71nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent