BDBM553444 4-(difluoromethyl)-N-[4- fluoro-5-[2-[rac-(3R)-3- methylmorpholin-4- yl]pyrimidin-5-yl]-2-[rac- (3S,5R)-3,4,5- trimethylpiperazin-1- yl]phenyl]-6-oxo-1H- pyridine-3-carboxamide::US11319299, Example 521::US11319299, Example 628

SMILES C[C@H]1CN(c2cc(F)c(-c3cnc(N4CCOC[C@@H]4C)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)F)CCN1C

InChI Key InChIKey=YXWUASKUCWSXGM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 553444   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553444BDBM553444(US11319299, Example 521 | US11319299, Example 628 ...)
Affinity DataKd:  0.579nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553444BDBM553444(US11319299, Example 521 | US11319299, Example 628 ...)
Affinity DataKd:  1.25nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent