BDBM553446 N-(cyclopropylmethyl)-4- [2-fluoro-5-[[1-methyl-6- oxo-4-(trifluoromethyl) pyridine-3-carbonyl]amino]-4- [rac-(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-1,3-thiazole-2- carboxamide::US11319299, Example 523

SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1cn(C)c(=O)cc1C(F)(F)F)-c1csc(n1)C(=O)NCC1CC1

InChI Key InChIKey=XKFXVWTTZHPMSW-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553446   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553446BDBM553446(N-(cyclopropylmethyl)-4- [2-fluoro-5-[[1-methyl-6-...)
Affinity DataKd:  4.59nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent