BDBM553484 N-[2-(4- cyclopropylpiperazin-1- yl)-4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 561

SMILES O=C(Nc1cc(-c2cnc(N3CCOCC3)nc2)c(F)cc1N1CCN(C2CC2)CC1)c1c[nH]c(=O)cc1C(F)(F)F

InChI Key InChIKey=RONIYNCQOSAEOQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553484   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553484BDBM553484(N-[2-(4- cyclopropylpiperazin-1- yl)-4-fluoro-5-(2...)
Affinity DataKd:  23.5nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent