BDBM553509 N-[4-fluoro-5-[2-[rac- (2R)-2-methylmorpholin- 4-yl]pyrimidin-4-yl]-2- [rac-(3S,5R)-3,4,5- trimethylpiperazin-1- yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 594

SMILES C[C@@H]1CN(c2cc(F)c(-c3ccnc(N4CCO[C@@H](C)C4)n3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C

InChI Key InChIKey=VWEOZFFYLTWZKK-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553509   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553509BDBM553509(N-[4-fluoro-5-[2-[rac- (2R)-2-methylmorpholin- 4-y...)
Affinity DataKd:  0.712nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent