BDBM553522 4-(difluoromethyl)-N-[4- fluoro-2-[rac-(3R)-3,4- dimethylpiperazin-1-yl]- 5-[2-[rac-(3R)-3- methylmorpholin-4- yl]pyrimidin-5- yl]phenyl]-1-methyl-6- oxopyridine-3-carboxamide::US11319299, Example 607

SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1cn(C)c(=O)cc1C(F)F)-c1cnc(nc1)N1CCOC[C@@H]1C

InChI Key InChIKey=LLGTXXNCAFAYRE-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553522   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553522BDBM553522(4-(difluoromethyl)-N-[4- fluoro-2-[rac-(3R)-3,4- d...)
Affinity DataKd:  1.53nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent