BDBM553527 4-(Difluoromethyl)-N-(4- fluoro-5-(1-(pyrrolidine- 1-carbonyl)-2,5-dihydro- 1H-pyrrol-3-yl)-2- ((3S,5R)-3,4,5- trimethylpiperazin-1- yl)phenyl)-6-oxo-1,6- dihydropyridine-3- carboxamide::US11319299, Example 612

SMILES C[C@@H]1CN(c2cc(F)c(C3=CCN(C(=O)N4CCCC4)C3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)F)C[C@H](C)N1C

InChI Key InChIKey=STRGPXZWGUVWDN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553527   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553527BDBM553527(4-(Difluoromethyl)-N-(4- fluoro-5-(1-(pyrrolidine-...)
Affinity DataKd:  1.94nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent