BDBM553537 4-(difluoromethyl)-N-[4- fluoro-5-(2-morpholin-4- yl-1,3-thiazol-4-yl)-2- [rac-(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-1-methyl-6- oxopyridine-3- carboxamide::US11319299, Example 622

SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1cn(C)c(=O)cc1C(F)F)-c1csc(n1)N1CCOCC1

InChI Key InChIKey=JLRJKTXPSSWJBZ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553537   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553537BDBM553537(4-(difluoromethyl)-N-[4- fluoro-5-(2-morpholin-4- ...)
Affinity DataKd:  5.15nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent