BDBM553551 3,3-Difluorocyclobutyl 3- (5-(4-(difluoromethyl)-6- oxo-1,6-dihydropyridine- 3-carboxamido)-2-fluoro- 4-((3S,5R)-3,4,5- trimethylpiperazin-1- yl)phenyl)-2,5-dihydro- 1H-pyrrole-1-carboxylate::US11319299, Example 637

SMILES C[C@@H]1CN(c2cc(F)c(C3=CCN(C(=O)OC4CC(F)(F)C4)C3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)F)C[C@H](C)N1C

InChI Key InChIKey=VTDBMBSOMILQMQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553551   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553551BDBM553551(3,3-Difluorocyclobutyl 3- (5-(4-(difluoromethyl)-6...)
Affinity DataKd:  2.26nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent