BDBM553553 (S)-N-(5-(1-(2- cyanopyrimidin-5-yl)- 1,2,3,6-tetrahydropyridin- 4-yl)-2-(3,4- dimethylpiperazin-1-yl)- 4-fluorophenyl)-4- (difluoromethyl)-6-oxo- 1,6-dihydropyridine-3- carboxamide::US11319299, Example 639

SMILES C[C@H]1CN(c2cc(F)c(C3=CCN(c4cnc(C#N)nc4)CC3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)F)CCN1C

InChI Key InChIKey=NQAPVMVOISWMGQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553553   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553553BDBM553553((S)-N-(5-(1-(2- cyanopyrimidin-5-yl)- 1,2,3,6-tetr...)
Affinity DataKd:  4.97nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent