BDBM553635 US11319299, Example 723::propan-2-yl 4-[5-[[4- (difluoromethyl)-6-oxo- 1H-pyridine-3- carbonyl]amino]-2- fluoro-4-[rac-(3R,5S)- 3,4,5-trimethylpiperazin- 1-yl]phenyl]-2,3,6,7- tetrahydroazepine-1- carboxylate

SMILES CC(C)OC(=O)N1CCC=C(c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)F)c(N3C[C@@H](C)N(C)[C@@H](C)C3)cc2F)CC1

InChI Key InChIKey=NGKBEYIANMQSOT-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553635   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553635BDBM553635(propan-2-yl 4-[5-[[4- (difluoromethyl)-6-oxo- 1H-p...)
Affinity DataKd:  3.12nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent