BDBM553636 US11319299, Example 724::propan-2-yl 4-[5-[[4- (difluoromethyl)-6-oxo- 1H-pyridine-3- carbonyl]amino]-2- fluoro-4-[rac-(3R)-3,4- dimethylpiperazin-1- yl]phenyl]-3,6-dihydro- 2H-pyridine-1-carboxylate

SMILES CC(C)OC(=O)N1CC=C(c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)F)c(N3CCN(C)[C@@H](C)C3)cc2F)CC1

InChI Key InChIKey=TVERYNURYMWSHK-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553636   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553636BDBM553636(propan-2-yl 4-[5-[[4- (difluoromethyl)-6-oxo- 1H-p...)
Affinity DataKd:  2.82nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent