BDBM553640 US11319299, Example 728::propan-2-yl 5-[2-fluoro- 5-[[4-fluoro-2- (trifluoromethyl)benzoyl] amino]-4-[rac-(3R)-3,4- dimethylpiperazin-1- yl]phenyl]-3,6-dihydro- 2H-pyridine-1-carboxylate

SMILES CC(C)OC(=O)N1CCC=C(c2cc(NC(=O)c3ccc(F)cc3C(F)(F)F)c(N3CCN(C)[C@@H](C)C3)cc2F)C1

InChI Key InChIKey=VWFZJHLHORFOES-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553640   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553640BDBM553640(propan-2-yl 5-[2-fluoro- 5-[[4-fluoro-2- (trifluor...)
Affinity DataKd:  3.55nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent