BDBM553655 N-[4-fluoro-5-[2-[rac- (2R,6S)-2,6- dimethylmorpholin-4- yl]pyrimidin-4-yl]-2-[rac- (3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-1-methyl-6- oxo-4-(trifluoromethyl) pyridine-3-carboxamide::US11319299, Example 743::US11319299, Example 745

SMILES C[C@H]1CN(C[C@@H](C)O1)c1nccc(n1)-c1cc(NC(=O)c2cn(C)c(=O)cc2C(F)(F)F)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=RJMONIVAVAQPFW-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 553655   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553655BDBM553655(US11319299, Example 743 | US11319299, Example 745 ...)
Affinity DataKd:  5.22nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553655BDBM553655(US11319299, Example 743 | US11319299, Example 745 ...)
Affinity DataKd:  5.60nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent