BDBM554117 US11325917, Compound I-9

SMILES Cc1cnc2c(N)c(sc2n1)C(=O)NCCc1ccc(N2CC3CCC(C2)N3)c(c1)C#N

InChI Key InChIKey=RNSWBPGWVLHLPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554117   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Valo Health

US Patent
LigandPNGBDBM554117(US11325917, Compound I-9)
Affinity DataIC50: 1.10E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP28 Activity: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Health

US Patent
LigandPNGBDBM554117(US11325917, Compound I-9)
Affinity DataIC50: 1.10E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP25 Activity: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent