BDBM554123 US11325917, Compound I-15

SMILES C[C@@H](CNC(=O)c1sc2nc(C)cnc2c1N)c1cc(F)c(cc1F)N1CC2CCC(C1)N2

InChI Key InChIKey=PJVZYGZSOPQNCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554123   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Valo Health

US Patent
LigandPNGBDBM554123(US11325917, Compound I-15)
Affinity DataIC50: 200nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP28 Activity: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Health

US Patent
LigandPNGBDBM554123(US11325917, Compound I-15)
Affinity DataIC50: 6.00E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP25 Activity: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent