BDBM554130 US11325917, Compound I-21

SMILES C[C@H](CNC(=O)c1sc2nc(C)cnc2c1N)c1cc(F)c(cc1F)N1CC2CNCC(C1)O2

InChI Key InChIKey=ATERIWMKTHLLIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554130   

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Health

US Patent
LigandPNGBDBM554130(US11325917, Compound I-21)
Affinity DataIC50: 1.10E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP25 Activity: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Valo Health

US Patent
LigandPNGBDBM554130(US11325917, Compound I-21)
Affinity DataIC50: 1.10E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP28 Activity: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent