BDBM557274 US11352354, Example V-c-39

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1Nc1nc(-c2ccncc2)c2[nH]ccc2n1

InChI Key InChIKey=DIIWJHSKXZYCBD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557274   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM557274(US11352354, Example V-c-39)
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to N-terminal His-tagged human PIKfyve expressed in Sf9 cells assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM557274(US11352354, Example V-c-39)
Affinity DataKd: >3.00E+7nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent