BDBM557835 US11365185, Example 17B

SMILES CC(C)Cc1cncc(Nc2c(-c3ccc(-c4ccc(C5(C(=O)O)CC5)cc4)cc3)cnn2C)n1

InChI Key InChIKey=YWVCNVGNWLTRMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557835   

TargetLysophosphatidic acid receptor 1(Human)
Eli Lilly

US Patent
LigandChemical structure of BindingDB Monomer ID 557835BDBM557835(US11365185, Example 17B)
Affinity DataIC50: 54.7nMAssay Description:A cDNA encoding the human LPAR1 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U937 cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetLysophosphatidic acid receptor 3(Human)
Eli Lilly

US Patent
LigandChemical structure of BindingDB Monomer ID 557835BDBM557835(US11365185, Example 17B)
Affinity DataIC50: 1.83E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent