BDBM557859 5-[2-cyclopropyl-3-[2-(trifluoromethoxy)ethyl]benzimidazol-5-yl]-1-methyl-3-(trifluoromethyl)pyridin-2-one ::US11365186, Compound 13

SMILES Cn1cc(cc(c1=O)C(F)(F)F)-c1ccc2nc(C3CC3)n(CCOC(F)(F)F)c2c1

InChI Key InChIKey=KWKRKUUBTCJVSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557859   

TargetBromodomain-containing protein 4 [49-170](Human)
Epigenetix

US Patent
LigandPNGBDBM557859(US11365186, Compound 13 | 5-[2-cyclopropyl-3-[2-(t...)
Affinity DataIC50: 810nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent