BDBM558745 Isomer-1 of 1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-3-(2-::US11365205, Example 16a

SMILES Cc1ccccc1CN1CCN(C[C@H](O)CN2CCc3ccccc3C2)C1=O

InChI Key InChIKey=ZVKLVILRBQJVIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558745   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 558745BDBM558745(Isomer-1 of 1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)...)
Affinity DataIC50: 190nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent