BDBM558771 4-((3-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-oxo-::US11365205, Example 37

SMILES Cc1cc(CN2CCN(CC(O)CN3CCc4ccccc4C3)C2=O)ccc1C#N

InChI Key InChIKey=BWTKHNCZAQPMFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558771   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558771(4-((3-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  80nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent