BDBM558771 4-((3-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-oxo-::US11365205, Example 37
SMILES Cc1cc(CN2CCN(CC(O)CN3CCc4ccccc4C3)C2=O)ccc1C#N
InChI Key InChIKey=BWTKHNCZAQPMFV-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 558771
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies
US Patent
Aurigene Discovery Technologies
US Patent
Affinity DataIC50: 80nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair