BDBM558788 (R)-1-((5-(4-acetylpiperazine-1-carbonylpyridin-2-yl)methyl)-3-(3-(3,4-::US11365205, Example 55

SMILES CC(=O)N1CCN(CC1)C(=O)c1ccc(CN2CCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)nc1

InChI Key InChIKey=MLWKLLNSKSSREI-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558788   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558788((R)-1-((5-(4-acetylpiperazine-1-carbonylpyridin-2-...)
Affinity DataIC50:  60nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent