BDBM558797 1-((5-(3-oxa-8-azabicyclo[3.2.1]octane-8-carbonyl)pyridin-2-yl)methyl)-3-((R)-::US11365205, Example 64

SMILES O[C@@H](CN1CCN(Cc2ccc(cn2)C(=O)N2C3CCC2COC3)C1=O)CN1CCc2ccccc2C1

InChI Key InChIKey=UZDTZSGMXJAHPA-NRUKRLKBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558797   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558797(1-((5-(3-oxa-8-azabicyclo[3.2.1]octane-8-carbonyl)...)
Affinity DataIC50:  70nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent