BDBM558804 (R)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-3-45-(pyrrolidin-::US11365205, Example 71
SMILES O[C@@H](CN1CCN(Cc2ccc(cn2)S(=O)(=O)N2CCCC2)C1=O)CN1CCc2ccccc2C1
InChI Key InChIKey=FILYWHWELPBJFG-HSZRJFAPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 558804
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies
US Patent
Aurigene Discovery Technologies
US Patent
Affinity DataIC50: 50nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair