BDBM559646 US11370803, Compound I-12

SMILES CC(NCc1ncn2ccc(Cl)c(F)c12)c1cn(Cc2cn3cc(ccc3n2)C2CC2)nn1

InChI Key InChIKey=VGYSRFBNROEPPZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559646   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM559646(US11370803, Compound I-12)
Affinity DataEC50:  125nMAssay Description:Inhibitory Activity of Exemplary Compounds against Plasma Kallikrein. Example compounds were evaluated for inhibition of the human activated kallikre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent