BDBM5597 3-Phenyl-5-(acetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 5a::N-{4-oxo-3-phenyl-2H,4H-indeno[1,2-c]pyrazol-5-yl}acetamide

SMILES CC(=O)Nc1cccc2-c3[nH]nc(c3C(=O)c12)-c1ccccc1

InChI Key InChIKey=FMWUPJJFWGHUDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5597   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5597(N-{4-oxo-3-phenyl-2H,4H-indeno[1,2-c]pyrazol-5-yl}...)
Affinity DataIC50: 240nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5597(N-{4-oxo-3-phenyl-2H,4H-indeno[1,2-c]pyrazol-5-yl}...)
Affinity DataIC50: 840nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed