BDBM561346 2-[4-[3-Chloro-4-[(4-chloropyridin-2-yl)methoxy]benzoyl]piperazin-1-yl]-3H-quinazolin-4-one::US11390610, Example 175

SMILES Clc1ccnc(COc2ccc(cc2Cl)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1

InChI Key InChIKey=GFTJRWUNSWOILU-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561346   

TargetMonoglyceride lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM561346(2-[4-[3-Chloro-4-[(4-chloropyridin-2-yl)methoxy]be...)
Affinity DataIC50:  48nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent