BDBM562583 2-(4-((2-(2,5-Dichlorophenyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-4-yl)amino)phenyl)acetamide hydrochloride::US11401286, Example 155

SMILES NC(=O)Cc1ccc(Nc2cc(nc3CCCc23)-c2cc(Cl)ccc2Cl)cc1

InChI Key InChIKey=ZZTFLBCBCAPOSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562583   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Human)
Tetra Discovery Partners

US Patent
LigandPNGBDBM562583(US11401286, Example 155 | 2-(4-((2-(2,5-Dichloroph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
US Patent

TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Tetra Discovery Partners

US Patent
LigandPNGBDBM562583(US11401286, Example 155 | 2-(4-((2-(2,5-Dichloroph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
US Patent