BDBM562609 4-[3-(cyanomethyl)-3- (3',5'-dimethyl-1H,1'H- 4,4'-bipyrazol-1- yl)azetidin-1-yl]-2,5- difluoro-N-[(1S)-2,2,2- trifluoro-1- methylethyl]benzamide::US11406640, Comp. No. 4

SMILES C[C@H](NC(=O)c1cc(F)c(cc1F)N1CC(CC#N)(C1)C1N=CC(=N1)c1c(C)n[nH]c1C)C(F)(F)F

InChI Key InChIKey=MIEKCABDTLFAAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562609   

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM562609(US11406640, Comp. No. 4 | 4-[3-(cyanomethyl)-3- (3...)
Affinity DataIC50: 300nMAssay Description:JAK1 pathway inhibitors that can be used for the treatment of cytokine-related diseases or disorders are tested for inhibitory activity of JAK target...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
US Patent