BDBM562827 (5R,6S)-6-(3-Chlorophenyl)-5-(4-chlorophenyl)-4-isopropylthiomorpholin-3-one::US11407721, Example 74

SMILES CC(C)N1[C@@H]([C@@H](SCC1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key InChIKey=VKUFOQXIICORFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562827   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 562827BDBM562827(US11407721, Example 74 | (5R,6S)-6-(3-Chlorophenyl...)
Affinity DataIC50: 1.68E+3nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent