BDBM563325 2-(8-(cyanomethyl)-6-{[(2-hydroxyethyl)amino]methyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)-6-(2,3-dihydro-1,4-benzodioxin-6-yl)benzonitrile::US11407749, Example 27

SMILES OCCNCc1cc(CC#N)c2nc(nn2c1)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

InChI Key InChIKey=AJMQWAZRWYKEIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563325   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM563325(2-(8-(cyanomethyl)-6-{[(2-hydroxyethyl)amino]methy...)
Affinity DataIC50: <100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent