BDBM563508 8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)-2- azaspiro[4.5]dec-7-ene- 3-carboxylic acid::US11407763, Example 80::US11407768, Compound 37

SMILES Cc5ccn(c1cc(Cl)ccc1[C@@H](Oc4cc(C2=CCC3(CC2)C[NH2+]C(C(=O)O)C3)nc(N)n4)C(F)(F)F)n5

InChI Key InChIKey=FYIVJIFZXFDCGP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563508   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 563508BDBM563508(US11407763, Example 79)
Affinity DataIC50: 185nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
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Date in BDB:
11/5/2022
Entry Details
US Patent