BDBM5638 3-(3-Methylthien-2-yl)-5-(acetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 13u::N-[3-(3-methylthiophen-2-yl)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl]acetamide

SMILES CC(=O)Nc1cccc2-c3n[nH]c(-c4sccc4C)c3C(=O)c12

InChI Key InChIKey=FGMFUNRHGWNTBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5638   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5638(N-[3-(3-methylthiophen-2-yl)-4-oxo-2H,4H-indeno[1,...)
Affinity DataIC50: 260nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5638(N-[3-(3-methylthiophen-2-yl)-4-oxo-2H,4H-indeno[1,...)
Affinity DataIC50: 3.10E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed