BDBM564192 US11414384, Example 104 Isomer 2::US11414384, Example 83 Isomer 1

SMILES Cn1cc(-c2ccc3c(C(=O)[C@H](NCCc4ccc(Cl)cc4)c4ccccc4)c[nH]c3c2)cn1

InChI Key InChIKey=PREKJLYPZPHGBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 564192   

LigandChemical structure of BindingDB Monomer ID 564192BDBM564192(US11414384, Example 83 Isomer 1 | US11414384, Exam...)
Affinity DataIC50: 388nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 564192BDBM564192(US11414384, Example 83 Isomer 1 | US11414384, Exam...)
Affinity DataIC50: 1.31E+3nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent