BDBM5648 3-(5-Carboethoxythien-2-yl)-5-(carbamoylamino)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 24h::ethyl 5-[5-(carbamoylamino)-4-oxo-2H,4H-indeno[1,2-c]pyrazol-3-yl]thiophene-2-carboxylate

SMILES CCOC(=O)c1ccc(s1)-c1[nH]nc2-c3cccc(NC(N)=O)c3C(=O)c12

InChI Key InChIKey=DKMYTSDWCTZOQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5648   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5648(3-(5-Carboethoxythien-2-yl)-5-(carbamoylamino)inde...)
Affinity DataIC50: 130nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5648(3-(5-Carboethoxythien-2-yl)-5-(carbamoylamino)inde...)
Affinity DataIC50: 300nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2005
Entry Details Article
PubMed