BDBM568104 US11420970, Example 306

SMILES COc1ccc(cc1F)-c1cc(Cn2cnc3c(N)ncnc23)c(cn1)N1C[C@H](N)C[C@@H](CF)C1

InChI Key InChIKey=XCNOJYKALJIDBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568104   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 568104BDBM568104(US11420970, Example 306)
Affinity DataIC50: 525nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent