BDBM568116 US11420970, Example 318

SMILES N[C@@H]1CCCN([C@@H]1C(N)=O)c1cnc(cc1Cn1cnc2c(N)ncnc12)-c1ccc(F)c(F)c1

InChI Key InChIKey=HXEOVCBFLIZDEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568116   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 568116BDBM568116(US11420970, Example 318)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent