BDBM570838 US11440899, Example 105::US11440899, Example 42

SMILES COc1nc(Nc2cc(ncn2)-c2ccc(OC3CCN(CC3)C(=O)OC(C)(C)C)c(c2)C#N)ccc1C(=O)N(C)C

InChI Key InChIKey=LJPVNMQWTKVBON-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 570838   

TargetSerine/threonine-protein kinase TBK1(Human)
Merck Patent

US Patent
LigandPNGBDBM570838(US11440899, Example 105 | US11440899, Example 42)
Affinity DataIC50: 100nMAssay Description:Test compounds were transferred into Labcyte polypropylene 384 well plates (P055-25) and diluted to 3 mM using DMSO. 3 mM test compounds were dispens...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

LigandPNGBDBM570838(US11440899, Example 105 | US11440899, Example 42)
Affinity DataIC50: 100nMAssay Description:Test compounds were transferred into Labcyte polypropylene 384 well plates (P055-25) and diluted to 3 mM using DMSO. 3 mM test compounds were dispens...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

LigandPNGBDBM570838(US11440899, Example 105 | US11440899, Example 42)
Affinity DataIC50: 100nMAssay Description:Test compounds were transferred into Labcyte polypropylene 384 well plates (P055-25) and diluted to 3 mM using DMSO. 3 mM test compounds were dispens...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase TBK1(Human)
Merck Patent

US Patent
LigandPNGBDBM570838(US11440899, Example 105 | US11440899, Example 42)
Affinity DataIC50: 100nMAssay Description:Test compounds were transferred into Labcyte polypropylene 384 well plates (P055-25) and diluted to 3 mM using DMSO. 3 mM test compounds were dispens...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent