BDBM571393 4-chloro-N-(4-(((3aR,6aS)-tetrahydro-1H-furo[3,4-c]pyrrol-5(3H) 1)methyl)phenyl)benzamide ::US11440918, Compound 10

SMILES Clc1ccc(cc1)C(=O)Nc1ccc(CN2C[C@@H]3COC[C@@H]3C2)cc1

InChI Key InChIKey=SWMHKOFWQMQSFJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 571393   

TargetSpike glycoprotein(2019-nCoV)
Gen1E Lifesciences

US Patent
LigandPNGBDBM571393(4-chloro-N-(4-(((3aR,6aS)-tetrahydro-1H-furo[3,4-c...)
Affinity DataIC50: 200nMAssay Description:After infection, supernatants were removed, and cells were fixed with 4% formaldehyde for 24 hours prior to being removed from the BSL-3 facility. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetSpike glycoprotein(2019-nCoV)
Gen1E Lifesciences

US Patent
LigandPNGBDBM571393(4-chloro-N-(4-(((3aR,6aS)-tetrahydro-1H-furo[3,4-c...)
Affinity DataIC50: 1.30E+3nMAssay Description:Cells were seeded in 24-well plates at a concentration of 7.5×104 cells/well. The following day, serial dilutions were performed in serum-free MEM me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetSpike glycoprotein(2019-nCoV)
Gen1E Lifesciences

US Patent
LigandPNGBDBM571393(4-chloro-N-(4-(((3aR,6aS)-tetrahydro-1H-furo[3,4-c...)
Affinity DataIC50: 2.80E+3nMAssay Description:The SARS-CoV-2 isolate BetaCoV/France/IDF0372/2020 (SARS-CoV-2 Paris) was supplied by the National Reference Centre for Respiratory Viruses hosted by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent