BDBM571394 4-chloro-N-(4-((4-hydroxypiperidin-1-yl)methyl)phenyl)benzamide ::US11440918, Compound 11

SMILES OC1CCN(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)CC1

InChI Key InChIKey=NXKXPJYOCHSEGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 571394   

TargetSpike glycoprotein(2019-nCoV)
Gen1E Lifesciences

US Patent
LigandPNGBDBM571394(4-chloro-N-(4-((4-hydroxypiperidin-1-yl)methyl)phe...)
Affinity DataIC50: 200nMAssay Description:After infection, supernatants were removed, and cells were fixed with 4% formaldehyde for 24 hours prior to being removed from the BSL-3 facility. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetSpike glycoprotein(2019-nCoV)
Gen1E Lifesciences

US Patent
LigandPNGBDBM571394(4-chloro-N-(4-((4-hydroxypiperidin-1-yl)methyl)phe...)
Affinity DataIC50: 1.60E+3nMAssay Description:Cells were seeded in 24-well plates at a concentration of 7.5×104 cells/well. The following day, serial dilutions were performed in serum-free MEM me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetSpike glycoprotein(2019-nCoV)
Gen1E Lifesciences

US Patent
LigandPNGBDBM571394(4-chloro-N-(4-((4-hydroxypiperidin-1-yl)methyl)phe...)
Affinity DataIC50: 2.10E+3nMAssay Description:The SARS-CoV-2 isolate BetaCoV/France/IDF0372/2020 (SARS-CoV-2 Paris) was supplied by the National Reference Centre for Respiratory Viruses hosted by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent