BDBM57165 2-(2-chlorophenyl)-5-methyl-4-[[2-(4-phenyl-2-oxazolin-2-yl)pyrrol-1-yl]methyl]oxazole::2-(2-chlorophenyl)-5-methyl-4-[[2-(4-phenyl-4,5-dihydro-1,3-oxazol-2-yl)pyrrol-1-yl]methyl]-1,3-oxazole::2-(2-chlorophenyl)-5-methyl-4-[[2-(4-phenyl-4,5-dihydrooxazol-2-yl)-1-pyrrolyl]methyl]oxazole::MLS000520215::SMR000130628::cid_9551168

SMILES Cc1oc(nc1Cn1cccc1C1=NC(CO1)c1ccccc1)-c1ccccc1Cl

InChI Key InChIKey=VOGUHDWNNPRBEF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 57165   

LigandChemical structure of BindingDB Monomer ID 57165BDBM57165(cid_9551168 | MLS000520215 | SMR000130628 | 2-(2-c...)
Affinity DataIC50: 4.66E+4nMAssay Description:Inhibition of human SHIP-1 (397 to 715 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using 1-(1,2-dioctanoylphosphatidyl) inositol-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 57165BDBM57165(cid_9551168 | MLS000520215 | SMR000130628 | 2-(2-c...)
Affinity DataEC50:  5.00E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 57165BDBM57165(cid_9551168 | MLS000520215 | SMR000130628 | 2-(2-c...)
Affinity DataIC50: 1.16E+5nMAssay Description:Inhibition of human SHIP-2 (420 to 732 residues) catalytic domain expressed in Rosetta DE3 BL21 cells using -(1,2-dioctanoylphosphatidyflinosito1-3,4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed