BDBM572039 (R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 4

SMILES Fc1ccc2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1

InChI Key InChIKey=DWWSHEDDRAZIRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 572039   

LigandChemical structure of BindingDB Monomer ID 572039BDBM572039((R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)piper...)
Affinity DataIC50: 6.50E+4nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 572039BDBM572039((R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)piper...)
Affinity DataIC50: 6.50E+4nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent