BDBM572056 (R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 21

SMILES CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(cc2n1)S(C)(=O)=O

InChI Key InChIKey=PWFBWQNBRPTGSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 572056   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 572056BDBM572056((R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Kinnate Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 572056BDBM572056((R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 572056BDBM572056((R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)...)
Affinity DataIC50: 6.50E+4nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent