BDBM572241 3-[4-(1,8- diazaspiro[5.5]undecan- 8-yl)-1H-pyrrolo[2,3- b]pyridin-3- yl]isothiazole::US11447505, Example E121
SMILES C1CCC2(CCCN(C2)c2ccnc3[nH]cc(-c4ccsn4)c23)NC1
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 572241
Affinity DataKi: 0.0490nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
Affinity DataKi: 386nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair