BDBM572266 US11447505, Example E41

SMILES N[C@@]1(CCCN(C1)c1ccnc2[nH]cc(-c3ccncn3)c12)NC1CC1

InChI Key InChIKey=NLCAMNKZRYBJFY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 572266   

TargetSerine/threonine-protein kinase MRCK beta(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM572266(US11447505, Example E41)
Affinity DataKi:  0.202nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2022
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM572266(US11447505, Example E41)
Affinity DataKi:  34.4nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2022
Entry Details
US Patent